Adobe Reader install fails (4 trys)

When installing an update (install_reader10_en_mssa_aih.exe) it fails givinge me an error saying it cannot access C:/Config.Msi.
Several times I have tried corrected the permissions to that directory only to find at some point during the install the permissions get changed and ownership becomes "unable to display current owner" and the install errors out.
I have many documents I access thru reader and now I cannot access any because the install, apparently, deleted the prior version. Help!
Thanks,
John

Thanks -- you pointed to a solution but a simpler one worked.
1. Changed Config.Msi name to Config.Msi.Old
2. Shut down all running apps including those started at start-up (but not including any services or background programs).
3. Re-ran install successfully.

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