Adobe Reader XI use 100 % of the processor in Internet Explorer

We have sequenced Adobe Reader XI with App-V 5.0 SP2 hotfix 5. This package is deployed in our Windows 2008 R2 Citrix XenApp 7.6 server. When we open a PDF document in Internet Explorer, after about 10 seconds IE freeze and this process use 100% of one processor.
The first 10 seconds, we can do watever we want with the PDF file.
We are searching a fix for this problem for many weaks, with no success. We have virtualized Adobe Reader X and we have no problem with PDF in Internet Explorer.
I know that installing Reader localy will solve the problem, but we want to virtualised the maximum of application without installing it natively.
Thanks for your help!

I have run a procmon and i have discover that when the processor is 100%, the Internet Explorer process query the registry with those key to the infinite :
14:21:54.1307690 IEXPLORE.EXE 7800 RegQueryKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37 SUCCESS Query: HandleTags, HandleTags: 0x100
14:21:54.1307944 IEXPLORE.EXE 7800 RegOpenKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37\Registry\User\S-1-5-21-854245398-789336058-725345543-8900_Classes\Local Settings\MuiCache\1FB\D9B7F780 NAME NOT FOUND Desired Access: Maximum Allowed
14:21:54.1308273 IEXPLORE.EXE 7800 RegQueryKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37\Versions\4679E4EB-4D2A-4D8F-9CB8-481E6FEFBC20 SUCCESS Query: HandleTags, HandleTags: 0x100
14:21:54.1308517 IEXPLORE.EXE 7800 RegOpenKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37\Versions\4679E4EB-4D2A-4D8F-9CB8-481E6FEFBC20\Registry\User\S-1-5-21-854245398-789336058-725345543-8900_Classes\Local Settings\MuiCache\1FB\D9B7F780 NAME NOT FOUND Desired Access: Maximum Allowed
14:21:54.1308819 IEXPLORE.EXE 7800 RegOpenKey HKU\S-1-5-21-854245398-789336058-725345543-8900_Classes\Local Settings\MuiCache\1FB\D9B7F780 SUCCESS Desired Access: Maximum Allowed, Granted Access: Read, Create Link
14:21:54.1309094 IEXPLORE.EXE 7800 RegSetInfoKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\Local Settings\MuiCache\1FB\D9B7F780 SUCCESS KeySetInformationClass: KeySetHandleTagsInformation, Length: 0
14:21:54.1309478 IEXPLORE.EXE 7800 RegQueryKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37 SUCCESS Query: HandleTags, HandleTags: 0x100
14:21:54.1309732 IEXPLORE.EXE 7800 RegCreateKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\AppV\Client\Packages\E9C21601-2C25-4417-92E9-35A059B30C37\Registry ACCESS DENIED Desired Access: Maximum Allowed
14:21:54.1310056 IEXPLORE.EXE 7800 RegCloseKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\Local Settings\MuiCache\1FB\D9B7F780 SUCCESS
14:21:54.1310313 IEXPLORE.EXE 7800 RegEnumKey HKU\S-1-5-21-854245398-789336058-725345543-8900_CLASSES\Local Settings\MuiCache\1FB SUCCESS Index: 0, Name: D9B7F780
Thanks!

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