After I have migrated a 'master' profile into another, the browse button (for a download location) in Options, General doesn't work anymore. How can I fix this?

Hi Supporters,
I've been struggling with this some time (downloading / saving problems) and tried all kinds of variations. But I'll keep it simple for now.
As a test .. I've just created a fresh firefox profile. Checked out if could change the download location, through the Browse button, and indeed that worked. I got an explorer dialog to choose a folder.
Normally I would do the options, manage the search engines, do some layout stuff etc etc in order to get some 'baseline / master' profile I can evolve further into other more extended profiles. So you see this master profile will get copied into another one.
But, having copied that fresh profile (having done nothing yet) into another seems to disable choosing another download folder. The Browse button in Options > General does not work anymore.
There's more. If I browse to, say, C:\ as default download location but then enable 'ask me where to save ..' in the fresh profile and then copy this profile to another one .. if I then want to change the download location (which shows C:) it jumps to Desktop and again the Browse button won't work.
This is driving me mad. Any ideas? Sorry for the long story, hope it helps.

Hi guys,
@cor-el: getting rid of not needed parts is what I always do. Besides prefs and localstore, only the search-metadata and permissions / signons are passed along. Oh, forgot to mention the mimetypes.
No, my point is why is FF looking for those folders when there's no mentioning of these to be found in my options? Not even in de about:config ... When I state C:\ as my downloads location it's absurd to check any other folder first, which FF seems to do before giving me an explorer window showing .. C:\ as a starting point. Like my unrestricted laptop does.
@jscher2000: Even if there are pointers to those default folders, FF should not be checking those. When I state C: I mean C: (see my answer above).
No, I'm convinced this is a bug unless someone knows a way to stop that folder checking. And to be honest, the not working Browse button is the least of my problems (I use: ask everytime where). No it's the saving that is the problem. But I guess the underlying problem is the same. Saving / downloading, what's in a name ..
Guys, thanks for your help ! I can't fix a bug so I'm going to let it be. I'll rebuild my master and will keep checking of saving a website becomes a problem somewhere. Mind you, the solutions offered in kb.mozillazine.org/Unable_to_save_or_download_files didn't work.
Oh well, I'll keep my fingers crossed :)

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