After upgrade to 10.5.2 Itunes wont start can't acces Itunes or Icloud

After upgrading my Itunes I can't open Itunes I have the uninstall and install for 3 times and does not work not even on safe mode... please help

I have the same problem.  One blog said to right click on iTunes and select Run as Administrator.  That worked, but only on that launch.  When I closed and tried to launch again, it does nothing.

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