All JCO's Disabled

Dear All,
Till yesterday we were having around 100 concurrent portal users and portal was running fine, as sson as the user base went to 300 the portal started giving 500 internal server error.
Our basis persons optimised the R/3 and set max users to 1000 and in EP in the Config tool there tried to increase the Server Node and restarted the cluster.
Due to which now the portal is not working and we are getting the following error.
  com.sap.tc.webdynpro.services.exceptions.WDRuntimeException: Failed to resolve JCO destination name 'SAP_R3_SelfServiceGenerics_MetaData' in the SLD. No such JCO destination is defined in the SLD.
i checked SLD test it is up and seems to be fine, One thing i noticed that when i click Maintain JCO destinations all the JCO's are inactive in it and none of it is green.
How do i activate these JCo's again as previous, please guide.
Cheers!
SJ.

Hi
First check SLD connection. If it is fine then ok. If not,
Go with the - Maintain Jco destination and create all while copying the same names.
Once you created with the same names just complete all while pinging...
But your problem seems to be a performance issue...however that how you will have to do...
Regards

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