All media on iPhone gone and iTunes does not remember my phone

Reposting from the iPhone board:
iTunes thinks my iPhone 4s is a new phone and is asking me to set it up again when in actuality it has been synced with iTunes since the 14th.  Moreover, all the music, podcasts, and video have disappeared from the phone.  I am running OS X 10.6.8 and iTunes 10.5.
I recently set up a second iTunes library, and switched back to my original using the click+option method.
Other than that, I can't think of anything that has changed.
Has anyone else seen this? 
Is there a work around?

UPDATE:  So I ended up restoring the phone and starting over as if it were new... by that I mean I did not restore from a saved file.
IT DID IT AGAIN!!!  This past friday, I went to sync the phone, and it happened again.
iTunes thinks it is a new phone and wants me to set it up again!!!!
For some reason I have no option to restore from a saved image this time either.
Is this a defective phone? 
Are other people running Snow Lepoard having issues?
So I removed and reinstalled the Apple Mobile Device Service and reinstalled iTunes in a rueful atempt to make it better.
I can't have this happen again... I lost a lot of data - not to mention the time it takes to set up all the app's, folders and settings... 
Anyone???? 

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