All sound devices gone after upgrade to 10.8.5 - help!!

Hi There,
I recently upgraded to Mountain Lion 10.8.5 and have lost all my sound (doesn't work over the net nor iTunes etc. - in fact iTunes doesn't even play). This all seems to be because if I open 'Audio MIDI setup' it simply states 'no devices found on the system'
Besides the obvious time machine back to the previous OSX is there anything I can do (time machine is back to a drive in my office and I am away from this). I'm pretty annoyed this has happened, everything else seems fine, thanks, Jim

Back up all data.
Triple-click anywhere in the line below on this page to select it:
/Library/Preferences/Audio/com.apple.audio.SystemSettings.plist
Right-click or control-click the line and select 
Services ▹ Reveal
from the contextual menu.* A folder should open with an item selected. Move the selected file to the Trash. You may be prompted for your administrator password.
Reboot and recreate your settings in the Sound preference pane.
*If you don't see the contextual menu item, copy the selected text to the Clipboard (command-C). In the Finder, select
Go ▹ Go to Folder...
from the menu bar, paste into the box that opens (command-V). You won't see what you pasted because a line break is included. Press return.

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