An unknown error-can't open iTunes

iTunes wont launch..."an unknown error has occurred" but when I log off my name on my mac and enter guest, iTunes comes up and runs no problem. I tried disk utility and still no good. Getting an iPhone for fathers day...but need itunes. Can anyone help?

The -50 in that context can indicate damage to your Apple Application Support. (Apple Application Support is where single copies of program files used by multiple different Apple programs are stashed.) So I'd first try a repair install of your Apple Application Support.
Restart the PC.
If you've got XP: head into your Add or remove programs control panel, select Apple Application Support, click "Change" and then click "Repair".
If you've got Vista or 7: Head into your Uninstall a program control panel, select "Apple Application Support", and click "Repair".
Does the repair install go through okay? If so, does your iTunes start launching again?

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