Any fixes for system pref not responding after a few seconds in 10.7.4?

I'm openning System Preferences both from the dock and by clicking the black apple, it opens and stops responding after about 5 second and the beach ball of death appears.  Tried restarting the unit, safe boot, verify and repair disk and permissions. Always the same issue. HELP!

Running out of "moving parts"...
Two (last?) things to try. 
1. Instead of launching system preferences through the menu launch it explicitly by double clicking the app in /Applications.
2. Temporarily rename ~/Library/Preferences/ByHost.  For example, stick a 'x' on the end of it ("ByHostx").  I don't want you to delete ByHost.  Only temporarily rename it.  This is the last possible directly-related system preference data that could have a problem. 
If it still hangs after this I am not exactly sure what to pursue next.  It can't be a login item or launch agent since these are suppressed when booting in safe mode.  You deleted the system preference cache and plist.  ByHost is the only thing explicitly related in you home directory.
One other thing would be to open Console for all messages and see if anything gets displayed when launching system preferences.

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