Any known software conflicts with Leopard

I am really frustrated. I've been an exclusive mac user since 87. I have had major problems with leopard that remind me of the pre-OSX days. Apps hanging, crashing, not shutting down (and I'm talking Apple apps like Safari). My computer hangs on shut down while Updating Boot Caches (I've let the thing run over night hoping I was just being impatient.). I have even had some kernel panics. I've run disk utility, TechTool Pro, and DiskWarrior. When I run these apps, some times they find problems and sometimes they don't. The hardware checks are okay. I have done a clean install of Leopard. And of course, everything is up to date. I have even had trouble syncing with dotmac with the syncs getting out of sync and constantly asking me which one I want to keep.
I never, ever had these problems with Tiger.
My final guess is that maybe there is some rouge piece of software that doesn't work well with Tiger.
Is there a list.
Any help?
Ever so frustrated,
Paul

What you did was an erase and install.
Check with each application vendor for software compatibility. The way you can tell if an application is compatible is if the actual update is said to be compatible.
I.e, when it says:
10.4.x and above means 10.4.0 and 10.4.1 compatible.
10.4.x and 10.5.x and above it means 10.4.0 - 10.4.11, and 10.5.0, and 10.5.1 compatible. No assurance though exists for Intel compatibility, unless it says Application Universal in the Finder menu -> Get Info information about the application. Rosetta applications are typically PowerPC compatible, with dependence on PowerPC drivers and may not always work with Intel Macs.
10.4.x and 10.5.0 to 10.5.2 it means it is compatible with the most recent release. The Intel Mac disclaimer applies here as well.
10.4.x and 10.5.0 to 10.5.2 PowerPC and Universal means it will work with PowerPC and Intel Macs running Tiger and Leopard to present day.
10.3.x and above does not mean 10.4.x compatible, nor does it mean 10.5.x compatible. There are some exceptions if the software was developed within the framework of Rosetta.
Visit http://www.macupdate.com/ and http://www.versiontracker.com/ for the most current info on application compatibility. If there are any applications you are uncertain about their compatibility and want to make sure you remove them entirely, use http://www.appzapper.com/

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