Application Error, certain sites not showing everything and will not automatically open downloaded files

When I open Firefox I get the Application Error message "The instruction at "0x00000000" reference memory at "0x00000000". The memory could not be "read". Click on OK to terminate the program" Firefox does then open but parts of sites are missing such as videos or animations. checked the plugins and all are up to date. Tried unistalling and re-installing Firefox but get the same error. Also when I download files and click open it doesnt open them, I have to go to the file location and open it. Started when I updated to version 3.6.6. IE8 works fine.
== This happened ==
Every time Firefox opened
== I upgraded to version 3.6.6 ==
== User Agent ==
Mozilla/4.0 (compatible; MSIE 8.0; Windows NT 5.1; Trident/4.0; InfoPath.2; .NET CLR 2.0.50727; .NET CLR 3.0.4506.2152; .NET CLR 3.5.30729)

Hi,
For IE,
You can also refer to the following two links for troubleshooting.
Follow guides to delete the browser history, disable all add-ons or reset IE (you will lose some IE settings), run a safety scan.
http://support.microsoft.com/kb/956196
http://support.microsoft.com/kb/967897/en-us
What is the result now?
Yolanda Zhu
TechNet Community Support

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