Application Memory Issue - Running 10.9.2

I have run my Etrecheck report and here are the results. I'm hoping someone can assist in diagnosing what 3rd party culprit is causing my issues.
Hardware Information:
    MacBook Pro (13-inch, Mid 2012)
    MacBook Pro - model: MacBookPro9,2
    1 2.9 GHz Intel Core i7 CPU: 2 cores
    8 GB RAM
Video Information:
    Intel HD Graphics 4000 - VRAM: 1024 MB
System Software:
    OS X 10.9.2 (13C64) - Uptime: 24 days 13:3:59
Disk Information:
    APPLE HDD HTS541075A9E662 disk0 : (750.16 GB)
        EFI (disk0s1) <not mounted>: 209.7 MB
        Macintosh HD (disk0s2) / [Startup]: 749.3 GB (198.7 GB free)
        Recovery HD (disk0s3) <not mounted>: 650 MB
    HL-DT-ST DVDRW  GS41N 
USB Information:
    BUFFALO INC. HD-GDU3 2 TB
        Timeline Backup (disk2s1) /Volumes/Timeline Backup: 2 TB (734.07 GB free)
    Apple Inc. Apple Internal Keyboard / Trackpad
    Apple Inc. BRCM20702 Hub
        Apple Inc. Bluetooth USB Host Controller
    Apple Computer, Inc. IR Receiver
    Hewlett-Packard HP LaserJet Professional P1102w
    Mitsumi Electric Hub in Apple Extended USB Keyboard
        Mitsumi Electric Apple Extended USB Keyboard
    Apple Inc. FaceTime HD Camera (Built-in)
FireWire Information:
Thunderbolt Information:
    Apple Inc. thunderbolt_bus
Kernel Extensions:
    com.protectmac.kext.AntiVirus    (1.1.5)
Startup Items:
    CiscoVPN: Path: /System/Library/StartupItems/CiscoVPN
    NMTCPSettingsTuning: Path: /System/Library/StartupItems/NMTCPSettingsTuning
    HP IO: Path: /Library/StartupItems/HP IO
    HWNetMgr: Path: /Library/StartupItems/HWNetMgr
    HWPortDetect: Path: /Library/StartupItems/HWPortDetect
Launch Daemons:
    [System]    com.adobe.fpsaud.plist 3rd-Party support link
    [System]    com.adobe.SwitchBoard.plist 3rd-Party support link
    [System]    com.fitbit.galileod.plist 3rd-Party support link
    [System]    com.google.keystone.daemon.plist 3rd-Party support link
    [System]    com.microsoft.office.licensing.helper.plist 3rd-Party support link
    [invalid]    com.oracle.java.Helper-Tool.plist
    [System]    com.protectmac.AntiVirus.plist 3rd-Party support link
    [System]    com.quark.quarkupdate.plist 3rd-Party support link
    [System]    com.taoeffect.ispyd.plist 3rd-Party support link
    [System]    com.xrite.device.xrdd.plist 3rd-Party support link
Launch Agents:
    [System]    com.adobe.AAM.Updater-1.0.plist 3rd-Party support link
    [System]    com.adobe.CS5ServiceManager.plist 3rd-Party support link
    [System]    com.creativeinaustria.LetterOpener.OutlookPlugin.Agent.plist 3rd-Party support link
    [System]    com.google.keystone.agent.plist 3rd-Party support link
    [System]    com.hp.help.tocgenerator.plist 3rd-Party support link
    [invalid]    com.oracle.java.Java-Updater.plist
    [System]    com.quark.quarkupdate.agent.plist 3rd-Party support link
    [invalid]    com.samsung.AWPAgent.plist
    [System]    com.xrite.device.softwareupdate.plist 3rd-Party support link
    [System]    jp.co.canon.UFR2.BG.plist 3rd-Party support link
User Launch Agents:
    [not loaded]    com.adobe.AAM.Updater-1.0.plist 3rd-Party support link
    [not loaded]    com.adobe.ARM.[...].plist 3rd-Party support link
    [not loaded]    com.akamai.single-user-client.plist 3rd-Party support link
    [not loaded]    com.citrixonline.GoToMeeting.G2MUpdate.plist 3rd-Party support link
    [not loaded]    com.hp.printerAgent.plist 3rd-Party support link
    [not loaded]    com.microsoft.LaunchAgent.SyncServicesAgent.plist 3rd-Party support link
    [not loaded]    com.spotify.webhelper.plist 3rd-Party support link
User Login Items:
    Skype
    AdobeResourceSynchronizer
    iTunesHelper
    PocketMacForBlackBerry
    Microsoft Database Daemon
    VMware Fusion Start Menu
    Dropbox
    Boingo Wi-Finder
    ProtectMacAntiVirusAgent
Internet Plug-ins:
    o1dbrowserplugin: Version: 5.2.4.18058 3rd-Party support link
    Default Browser: Version: 537 - SDK 10.9
    Flip4Mac WMV Plugin: Version: 2.1.2.72 3rd-Party support link
    OfficeLiveBrowserPlugin: Version: 12.2.6 3rd-Party support link
    RealPlayer Plugin: Version: (null) 3rd-Party support link
    AdobePDFViewerNPAPI: Version: 10.1.9 3rd-Party support link
    FlashPlayer-10.6: Version: 12.0.0.77 - SDK 10.6 3rd-Party support link
    Silverlight: Version: 5.1.20913.0 - SDK 10.6 3rd-Party support link
    SlingPlayer: Version: (null) - SDK 10.6 3rd-Party support link
    Flash Player: Version: 12.0.0.77 - SDK 10.6 3rd-Party support link
    QuickTime Plugin: Version: 7.7.3
    googletalkbrowserplugin: Version: 5.2.4.18058 3rd-Party support link
    iPhotoPhotocast: Version: 7.0
    AdobePDFViewer: Version: 10.1.9 3rd-Party support link
    SharePointBrowserPlugin: Version: 14.3.9 - SDK 10.6 3rd-Party support link
    WidevineMediaOptimizer: Version: 6.0.0.12607 - SDK 10.7 3rd-Party support link
    JavaAppletPlugin: Version: 14.9.0 - SDK 10.7 Outdated! Update
Safari Extensions:
    Slick Savings: Version: 1.0
    Searchme: Version: 1.3
    Amazon Shopping Assistant: Version: 1.1
    Ebay Shopping Assistant: Version: 1.1
Audio Plug-ins:
    BluetoothAudioPlugIn: Version: 1.0 - SDK 10.9
    AirPlay: Version: 2.0 - SDK 10.9
    AppleAVBAudio: Version: 203.2 - SDK 10.9
    iSightAudio: Version: 7.7.3 - SDK 10.9
iTunes Plug-ins:
    Quartz Composer Visualizer: Version: 1.4 - SDK 10.9
User Internet Plug-ins:
    CitrixOnlineWebDeploymentPlugin: Version: 1.0.105 3rd-Party support link
    WebEx64: Version: 1.0 - SDK 10.5 3rd-Party support link
3rd Party Preference Panes:
    Akamai NetSession Preferences  3rd-Party support link
    Flash Player  3rd-Party support link
    Flip4Mac WMV  3rd-Party support link
    HP Scanjet  3rd-Party support link
    Quark Update Preferences  3rd-Party support link
Old Applications:
    Microsoft Language Register:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        /Applications/Microsoft Office 2011/Additional Tools/Microsoft Language Register/Microsoft Language Register.app
    Set IP:    Version: 1.0.1 - SDK 10.5 3rd-Party support link
        /Users/[redacted]/Desktop/folder/PrinterDriver/MAC_Installer/MAC_Printer/SetIP/ Set IP.app
    SLLauncher:    Version: 1.0 - SDK 10.5 3rd-Party support link
        /Library/Application Support/Microsoft/Silverlight/OutOfBrowser/SLLauncher.app
    Solver:    Version: 1.0 - SDK 10.5 3rd-Party support link
        /Applications/Microsoft Office 2011/Office/Add-Ins/Solver.app
    H&R Block 2013:    Version: 1.4 - SDK 10.5 3rd-Party support link
    H&R Block 2011:    Version: 1.3 - SDK 10.4 3rd-Party support link
    H&R Block 2012:    Version: 1.10 - SDK 10.5 3rd-Party support link
    /Applications/Microsoft Office 2011
        Microsoft PowerPoint:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Excel:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Outlook:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Word:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Document Connection:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
    /Applications/Microsoft Office 2011/Office
        Microsoft Graph:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Database Utility:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Office Reminders:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Upload Center:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        My Day:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        SyncServicesAgent:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Open XML for Excel:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Alerts Daemon:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Database Daemon:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Chart Converter:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
        Microsoft Clip Gallery:    Version: 14.3.9 - SDK 10.5 3rd-Party support link
    Perfect Effects Free:    Version: 3.0.2 - SDK 10.5 3rd-Party support link
        /Applications/Perfect Effects Free/Perfect Effects Free.app
    /Users/[redacted]/Library/Application Support/WebEx Folder/1224
        Cisco WebEx Meeting Center:    Version: 11.24.32.0 - SDK 10.5 3rd-Party support link
        asannotation2:    Version: 8.25.31.0 - SDK 10.5 3rd-Party support link
        atmsupload:    Version: 4.14.29.0 - SDK 10.5 3rd-Party support link
        convertpdf:    Version: 1.2 - SDK 10.5 3rd-Party support link
    Microsoft AutoUpdate:    Version: 2.3.6 - SDK 10.4 3rd-Party support link
        /Library/Application Support/Microsoft/MAU2.0/Microsoft AutoUpdate.app
    Audacity:    Version: 2.0.2.0 - SDK 10.4 3rd-Party support link
        /Applications/Audacity/Audacity.app
    /Library/Application Support/Microsoft/MERP2.0
        Microsoft Error Reporting:    Version: 2.2.9 - SDK 10.4 3rd-Party support link
        Microsoft Ship Asserts:    Version: 1.1.4 - SDK 10.4 3rd-Party support link
    QuarkUpdate:    Version: 1.1.0.1 - SDK 10.5 3rd-Party support link
        /Library/Application Support/Quark/AutoUpdate/QuarkUpdate.app
    Set IP:    Version: 1.0.1 - SDK 10.5 3rd-Party support link
        /Users/[redacted]/Desktop/PrinterDriver/MAC_Installer/MAC_Printer/SetIP/Set IP.app
Time Machine:
    Skip System Files: NO
    Mobile backups: ON
    Auto backup: YES
    Volumes being backed up:
        Macintosh HD: Disk size: 697.84 GB Disk used: 512.78 GB
    Destinations:
        Timeline Backup [Local] (Last used)
        Total size: 2 
        Total number of backups: 35
        Oldest backup: 2013-10-06 20:07:55 +0000
        Last backup: 2014-03-28 19:36:19 +0000
        Size of backup disk: Adequate
            Backup size 2  > (Disk used 512.78 GB X 3)
    Time Machine details may not be accurate.
    All volumes being backed up may not be listed.
Top Processes by CPU:
        52%    System Preferences
         7%    Finder
         6%    com.apple.preferences.users.remoteservice
         6%    CVMCompiler
         5%    gamed
Top Processes by Memory:
    573 MB    systemstats
    401 MB    firefox
    279 MB    Finder
    74 MB    Mail
    66 MB    WindowServer
Virtual Memory Information:
    31 MB    Free RAM
    1.28 GB    Active RAM
    1.26 GB    Inactive RAM
    1.66 GB    Wired RAM
    201.07 GB    Page-ins
    6.79 GB    Page-outs

The message has nothing to do with low disk space.
There is excessive swapping of data between physical memory (that is, the memory chips on the logic board) and virtual memory (one or more files on the startup volume.) That activity is relatively slow and causes the whole system to be less responsive. It can happen for two reasons:
A long-running process with a memory leak (a kind of bug)
Not enough memory for your usage pattern
Tracking down a memory leak can be difficult, and it may come down to a process of elimination.
These instructions are for OS X 10.9 ("Mavericks.") The procedure may be slightly different for earlier versions of OS X.
When you notice the swap activity, open the Activity Monitor application and select All Processes from the View menu, if it's not already selected. Select the Memory tab. Click the heading of the Real Mem column in the process table twice to sort the table with the highest value at the top. If you don't see that column, select
View ▹ Columns ▹ Real Memory
from the menu bar.
If one process (excluding "kernel_task") is using much more memory than all the others, that could be an indication of a leak. A better indication would be a process that continually grabs more and more real memory over time without ever releasing it. Here is an example of how it's done.
The processes named "Safari Web Content" render web pages for Safari. They use a lot of memory and may leak if certain Safari extensions or third-party web plugins are installed. Consider them prime suspects.
Another process often implicated in memory leaks is "inkjet4" or "inkjet8," which is a component of the HP printing software. If it's present, force-quit the process in Activity Monitor to solve the problem temporarily. Empty the print queues in the Printers & Scanners preference pane (which has a slightly different name in each recent version of OS X.) If you don't use an HP printer, remove the software. Otherwise, if the problem is recurrent, update the software (which may not help) or contact HP support.
"Wired" memory should be a small part of the total. That memory is not swapped, but it makes less physical memory available which may then result in swapping. If you have a lot of wired memory, that's usually an indication of a memory leak in a third-party program that modifies the operating system at a low level. Ask for guidance in that case.
If you don't have an obvious memory leak, your options are to install more memory (if possible) or to run fewer programs simultaneously.
The next suggestion is only for users familiar with the shell. For a more precise, but potentially misleading, test, run the following command: 
sudo leaks -nocontext -nostacks process | grep total
where process is the name of a process you suspect of leaking memory. Almost every process will leak some memory; the question is how much, and especially how much the leak increases with time. I can’t be more specific. See the  leaks(1) man page and the Apple developer documentation for details.

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    Been using this Mac for good 6 months now, and one fine day of normal usage the whole system seems really laggy and slow and all of a sudden i'm unable to access anything and barely move my mouse. Then, a window pops out, telling me "Your system has run out of application memory", gracefully showing me that I have to force quit all my programmes for me to just stare at my desktop in utter disappointment.
    I've been using Yosemite for awhile now (updated few days since the release) and haven't encountered any major issues, this being the first. Reading through many threads many have said that the problem lies with opening the Mail app, yet I haven't touched that app in months. I've also tried resetting the PRAM on my machine when it happens and the problem comes back again after several minutes of normal usage (iTunes, App Store). Checking the memory usage with the Memory Clean app, it tells me I'm down to a measly '15.58 MB' of memory, and it justfluctuates at that until I give it a restart again. This can't keep happening - I can barely use the Mac for 10 minutes without having to restart it, only to be able to use it only again for another 10 minutes.
    Opening Activity Monitor tells me that mds_stores is the main root of the problem, yet I can't seem to shut the process down. I've googled and many say that mds_stores is spotlight indexing, but taking up all 16 GB of ram? That shouldn't be the case. Is there a fix to this? Does Apple know of its existence?
    Included some screenshots below:

    Step 1
    These instructions must be carried out as an administrator. If you have only one user account, you are the administrator.
    Triple-click anywhere in the line below on this page to select it:
    syslog -F '$Time $Message' -k Sender mdworker -o -k Message Rne Norm -k Sender mds | tail | pbcopy
    Copy the selected text to the Clipboard by pressing the key combination command-C.
    Launch the built-in Terminal application in any of the following ways:
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    ☞ Open LaunchPad and start typing the name.
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    The command may take a noticeable amount of time to run. Wait for a new line ending in a dollar sign ($) to appear.
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    The Terminal window doesn't show the output. Please don't copy anything from there.
    If any personal information appears in the output, anonymize before posting, but don’t remove the context.
    Step 2
    Enter the following command as in Step 1 and post the output:
    mdutil -as 2>&- | pbcopy
    You can then quit Terminal.
    Step 3
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              View ▹ Show Log List
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    Please don’t post any other kind of diagnostic report, such as hang logs—they're very long and not helpful.

  • I keep getting this notice: "your machine has run out of application memory". Why am I getting this message?

    Why do I keep getting the notice "your machine has run out of application memory"?
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    Well Carolyn
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  • TO NOKIA SUPPORT: Application Manager Memory issue...

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    So hope i.I'm preparing a bug report to post here.Maybe with our reports the new firmwares will be even better...if some Nokia guy is looking at what we're speaking
    Ever dreamed of earning money online without wasting a single cent?Now you can:
    http:// tinyurl.com/2pfgv2

  • Not enough memory to run Microsoft Excel. Please close other applications and try again.

    Hi All,
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    ====================
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    Tony Chen
    TechNet Community Support

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    http://liulab.dfci.harvard.edu/MACS/README.html
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