Applications in Mac Book Pro crash continuously

Question

Problem description:
Applications in Mac Book Pro crash continuously: Safari, Lightroom, Finder, eMail, Notes, Aperture, Excel….  I may work a few mins and than one or more applications get stuck. Sometimes I manage to force exit from the app, sometimes the procedure is unsuccessful and the beach ball never stop spinning. Rebooting is than necessary.  Noted this after upgratd to Yosemite OS, things went wrong especially after installing some net apps (Monity, Wifi Explorer, WiFi Signal, Network Radar)
EtreCheck version: 2.2 (132)
Report generated 4/23/15, 8:30 PM
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Click the [Click for details] links for more information about that line.
Hardware Information: ℹ️
    MacBook Pro (Retina, 15-inch, Early 2013) (Technical Specifications)
    MacBook Pro - model: MacBookPro10,1
    1 2.7 GHz Intel Core i7 CPU: 4-core
    16 GB RAM Not upgradeable
        BANK 0/DIMM0
            8 GB DDR3 1600 MHz ok
        BANK 1/DIMM0
            8 GB DDR3 1600 MHz ok
    Bluetooth: Good - Handoff/Airdrop2 supported
    Wireless:  en0: 802.11 a/b/g/n
    Battery: Health = Normal - Cycle count = 259 - SN = D863205Q0X4DNMHB6
Video Information: ℹ️
    Intel HD Graphics 4000
        Color LCD 2880 x 1800
    NVIDIA GeForce GT 650M - VRAM: 1024 MB
System Software: ℹ️
    OS X 10.10.3 (14D136) - Time since boot: 0:12:27
Disk Information: ℹ️
    APPLE SSD SD512E disk0 : (500,28 GB)
        EFI (disk0s1) <not mounted> : 210 MB
        Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
        Macintosh HD (disk1) / : 499.03 GB (87.33 GB free)
            Encrypted AES-XTS Unlocked
            Core Storage: disk0s2 499.42 GB Online
USB Information: ℹ️
    Apple Inc. FaceTime HD Camera (Built-in)
    Apple Inc. Apple Internal Keyboard / Trackpad
    Apple Inc. BRCM20702 Hub
        Apple Inc. Bluetooth USB Host Controller
Thunderbolt Information: ℹ️
    Apple Inc. thunderbolt_bus
Gatekeeper: ℹ️
    Mac App Store and identified developers
Kernel Extensions: ℹ️
        /Applications/ESET Cyber Security Pro.app
    [loaded]    com.eset.kext.esets_kac (600.01.40f01) [Click for support]
    [loaded]    com.eset.kext.esets_pfw (600.01.40f01) [Click for support]
        /Library/Extensions
    [not loaded]    foo.tap (1.0) [Click for support]
    [not loaded]    foo.tun (1.0) [Click for support]
        /System/Library/Extensions
    [not loaded]    com.wacom.kext.wacomtablet (6.3.7 - SDK 10.8) [Click for support]
Launch Agents: ℹ️
    [not loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
    [loaded]    com.oracle.java.Java-Updater.plist [Click for support]
Launch Daemons: ℹ️
    [loaded]    com.adobe.fpsaud.plist [Click for support]
    [running]    com.eset.esets_daemon.plist [Click for support]
    [loaded]    com.microsoft.office.licensing.helper.plist [Click for support]
    [loaded]    com.oracle.java.Helper-Tool.plist [Click for support]
    [loaded]    com.purevpn.macapp.plist [Click for support]
User Launch Agents: ℹ️
    [loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
    [not loaded]    com.google.keystone.agent.plist [Click for support]
    [running]    ws.agile.1PasswordAgent.plist [Click for support]
User Login Items: ℹ️
    iTunesHelper    Applicazione Hidden (/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
    Dropbox    Applicazione  (/Applications/Dropbox.app)
    ElementsAutoAnalyzer    UNKNOWN Hidden (missing value)
    ESET Cyber Security Pro    Applicazione  (/Applications/ESET Cyber Security Pro.app)
    ESET Cyber Security Pro    Applicazione  (/Applications/ESET Cyber Security Pro.app)
Internet Plug-ins: ℹ️
    AdobeExManDetect: Version: AdobeExManDetect 1.1.0.0 - SDK 10.7 [Click for support]
    FlashPlayer-10.6: Version: 17.0.0.169 - SDK 10.6 [Click for support]
    QuickTime Plugin: Version: 7.7.3
    Flash Player: Version: 17.0.0.169 - SDK 10.6 [Click for support]
    Default Browser: Version: 600 - SDK 10.10
    WacomNetscape: Version: 2.1.0-1 - SDK 10.8 [Click for support]
    SharePointBrowserPlugin: Version: 14.4.9 - SDK 10.6 [Click for support]
    PepperFlashPlayer: Version: 17.0.0.169 - SDK 10.6 [Click for support]
    Silverlight: Version: 5.1.30514.0 - SDK 10.6 [Click for support]
    WacomTabletPlugin: Version: WacomTabletPlugin 2.1.0.2 [Click for support]
    JavaAppletPlugin: Version: Java 8 Update 40 Check version
Safari Extensions: ℹ️
    1Password
    Video Converter
3rd Party Preference Panes: ℹ️
    Flash Player  [Click for support]
    Growl  [Click for support]
    Java  [Click for support]
    Akamai NetSession Preferences  [Click for support]
Time Machine: ℹ️
    Skip System Files: NO
    Mobile backups: ON
    Auto backup: YES
    Volumes being backed up:
        Macintosh HD: Disk size: 499.03 GB Disk used: 411.70 GB
    Destinations:
        Time Capsule (Hard Disc) [Network]
        Total size: 1.00 TB
        Total number of backups: 3
        Oldest backup: 2015-03-03 22:33:54 +0000
        Last backup: 2015-03-08 20:44:48 +0000
        Size of backup disk: Too small
            Backup size 1.00 TB < (Disk used 411.70 GB X 3)
Top Processes by CPU: ℹ️
         4%    WindowServer
         2%    fontd
         0%    taskgated
         0%    notifyd
         0%    esets_daemon(2)
Top Processes by Memory: ℹ️
    883 MB    kernel_task
    246 MB    com.apple.WebKit.WebContent(3)
    197 MB    mdworker(13)
    147 MB    WindowServer
    131 MB    Safari
Virtual Memory Information: ℹ️
    9.40 GB    Free RAM
    6.59 GB    Used RAM
    0 B    Swap Used
Diagnostics Information: ℹ️
    Apr 23, 2015, 08:23:12 PM    /Library/Logs/DiagnosticReports/esets_proxy_2015-04-23-202312_[redacted].crash
    Apr 23, 2015, 08:21:12 PM    /Library/Logs/DiagnosticReports/esets_proxy_2015-04-23-202112_[redacted].crash
    Apr 23, 2015, 08:16:59 PM    Self test - passed
    Apr 23, 2015, 08:30:38 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/PureVPN_2015-04-23-083038_[red acted].crash
    Apr 22, 2015, 11:44:57 PM    /Library/Logs/DiagnosticReports/Finder_2015-04-22-234457_[redacted].hang
    Apr 22, 2015, 11:44:54 PM    /Library/Logs/DiagnosticReports/Microsoft Excel_2015-04-22-234454_[redacted].hang
    Apr 20, 2015, 09:38:16 PM    /Library/Logs/DiagnosticReports/backupd_2015-04-20-213816_[redacted].cpu_resour ce.diag [Click for details]

Answer 1

Uninstall ESET Cyber Security Pro
Repair your drive and then do a Safe Boot at least once.
While not extremely low having only 20% free for an SSD can be an issue, again, running DU from another drive or Recovery would help.
When in doubt, clone, backup, and do a clean install. Setup Assistant will bring back what you want.
Should see this moved to MacBook Pro forum shortly.