Applications seem to be running slower on Lion & Mail doesn't work well

My applications like iPhoto, Safari, and Mail all seem  to be running slower and slower.  They were lightning-like right after I installed Lion, but now it seems to be running more slowly every day terrible.  Reloading a page or opening a new tab in Safari is Very S L O W....and iPhoto seems to go into a loop or something, and takes forever to come out of it. 
We also installed a Time Capsule, so maybe that's the problem, but does anyone else have suggestions on things we should do to improve performance?
The other - bigger - problem is sending mail.  I keep getting the message that "cannot send mail on the selected server,"  and that it has timed out.  It's the server I have been using, so I am baffled.  The name of the server is smtp.me.com:myusername 
Should I change it???  but to what????
Can you tell I'm a total novice at trouble-shooting?  Well...I am!  so I sure hope someone can help. 

That's assuming PS was build to not do it. Scratch disks and display tiles are a fundamental principle of the program and I don't consider them a workaround for anything. You know, over in the video apps forums we poor souls have been begging for years that After Effects would be half as smart as PS in that regard. I also tend to think that your alleged "do it all in RAM" would fall apart as soon as you begin to deal with a number of images and document sizes that exhaust that RAM. One might say that in foreseeable time RAM will be so dirt cheap, that 32GB machines will be commonplace even for home users, but it's not there yet. And then it's the question: Do I burn 1000 Watts of electricity even in idle state just to work on a monster machine with lots of RAM or do I use just 300 Watts on a normal system with a scratch disk and energy saving options. It's the same gag as with multicore processors or those monstrous graphics cards (Quadro CX, anyone?): the marketing may tell you, you need those things, but it must not necessarily do anything for your personal workflow. Those arguments really have no value if this Quadro CX has nothing to do most of the time or of 16 cores only 1 barely even peaks while you paint and likewise you wouldn't need those tons of RAM, if all you ever do is adjusting a few photos from digital cameras. You have to differentiate between "average" users and extreme "power users", but nowhere is it written that 1% of power users must or can dictate what's good for the 99% other users, a dilemma software devs face every day... I would tend to think that 64bit and its possible advantages are in fact very low on the list for those 99% of users, but other things are much more important to them.
Mylenium

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