Apps hang at splash screen and lock computer

I have tried to install indd and ai and both crash and lock the computer when I try and run them. The apps get as far as the spas screen then freeze.
Creative cloud
Macpro 10.7.5

Hey i think i figured it out.
Had the same prob. 10.6 12.2.1 entourage hanging.
Renamed FCT, instantly prompted that a font was corrupt. Removed the corrupt Font: KufiStandardGK.ttf << this just happened to be my one corrupt font.
A little troubleshooting i did leading up to this, I read your post and my situation was the same. I use Linotype X to manage fonts. I disabled all but the minimum fonts (i moved them into a folder font_trouble in the same folder)
I also deleted every office pref/plist setting i thought relevant to startup which triggered the microsoft setup assistant (watched via the console app) and it ran through its check and then immediately the fontcachetool started and went awol on cpu time. Once i killed it--during the starting up of word and entourage... timing may be unrelated but i did them at nearly the same time.
Ps. Your post was extremely well written and I apologize for my stream of consciousness, less than stelllar response... hope this helps if not feel free to ping me for more details on what I did...
Good Luck.. All my office apps are running normally now.

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    Hey i think i figured it out.
    Had the same prob. 10.6 12.2.1 entourage hanging.
    Renamed FCT, instantly prompted that a font was corrupt. Removed the corrupt Font: KufiStandardGK.ttf << this just happened to be my one corrupt font.
    A little troubleshooting i did leading up to this, I read your post and my situation was the same. I use Linotype X to manage fonts. I disabled all but the minimum fonts (i moved them into a folder font_trouble in the same folder)
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