Are there any programmatic means of reducing paging and increasing efficiency of insert/updates?

We have a multi-terabyte database which daily receives tens of thousands of records to insert or update. Most online advice on reducing memory paging covers server memory options and dynamic memory management techniques.
Are there any tested programmatic or database design techniques that could also be explored to increase efficiency?
Thanks,
Tom

> How long is it taking now to process this workload?
About four hours. The record data is inserted/updated across multiple related tables.
Across about how many tables?
Four hours seems a bit long for 100k rows to merge, say half updates and half new inserts (and whatever you do about deletes, maybe treat them as slowly changing dimensions), but my first move would be to just treat it as an optimization question and use
the profiler to get a list of the longest running and most expensive queries, and see if they can be individually improved.
Just basic stuff - do you handle the rows one at a time and commit for each one, or are the processes done relationally and with one commit per batch?
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Are there any programmatic means of reducing paging and increasing efficiency of insert/updates?

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