At start up, messase "could not initialise application's security component

My Grandson has a Toshiba laptop. When he attempts to start Firefox this message appears:
"Could not initialise the application's security component. The most likely cause is problems with files in your application's profile directory. Please check that this directory has no read/write restrictions & your hard disk is not full, or close to full. It is recommended that you exit the application andfix the problem. If youcontinue to use this session you might see incorrect application behaviour accessing security features."
Firefox does start, but just shows a blank page.
Can you advise what he should to eliminate the problem?
Thank you
Frank Howe

http://support.mozilla.com/en-US/kb/Could%20not%20initialize%20the%20browser%20security%20component
This will help fixing your problem!

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