Bootup hang and then some apps not launching

Bought magic mouse at weekend - installed OK and worked. Don't know if magic mouse relevant to problem- saw one thread which suggested reducing speed of double click to cure failure to launch app - tried this after the hang below and no difference - so the hang may be unrelated to new mouse.
Computer (late 2007) hung when booting up few days later. Sound and apple screen normal. Then hung on blue screen. Rebooted - same. Researched and started in safe mode - booted up to normal finder screen. Restarted - normal boot up but various apps eg mail, address book, quicktime, ical won't launch from either the dock or apps folder. Preview won't open file. In the dock icons move up and down jerkily then disappear. If launched from apps folder large pixellated app icon momentarily appears then vanishes. Some third party apps eg notebook launch normally from apps folder.
Have run disc utility from SL - no hard drive errors reported. Fixed permissions etc. No difference. Saw a note which said the SUID ? file had been changed but could not be repaired - don't know what that means. Have reset PRAM - no difference. Downloaded Onyx and SL combo update but neither will launch. Tried re-installing SL but this hung and would not instal with error message 10822 the operation cannot be completed. Computer generally running slowly and jerkily.
Help please! The extra RAM is Crucial and was installed about 9 months ago.

That indicates corruption or conflicts with 3rd-party things in the normal boot account. Create a new admin user account and see if that fixes the problem. As for QuickSilver and the scripts, that might indicate that they're in Login Items and usually mount on startup. I recommend deleting them from the login items. Also, check the various /Library/LaunchAgents/, /Library/LaunchDaemons/, and /Library/StartupItems/ for rogue processes. If you don't have the issues in this new account, then you can proceed in two ways. One is to log into your new account, make a list of the preference files (plists) located in /username/Library/Preferences/, including any in the ByHost subfolder, log back into the original account, move everything not on that list into a newly created folder on the Desktop, log out and back in, and see if the problem goes away. If so, you can copy the ones in the Desktop folder (one at time) back into /Preferences/, restart, and see if the problem returns. If so, you've identified the corrupt/conflicting one. Continue with all of them until isolating the bad ones. That'll save you the trouble of resetting preferences.
The second way is much more detailed and I'll not burden you with the steps unless the above doesn't fix the issue.

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Bootup hang and then some apps not launching

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