Bug when saving - files are all inverted and transparent

Hi there,
I've been working on a job for a few hours now and I have still have it open in photoshop CS5 extended.
Basically if I save it out in ANY format (tiff, psb, psd, jpg) it is inverted and the transparency is all messed up.. when I look at it in bridge or reopen it in photoshop or preview, it's the same.
I have the file still open in photoshop and I'm scared to close it because it looks just fine on screen but when I try to do anything it is behaving strangely. for example if I convert to CMYK it goes to the inverted image which it saves out.
I deleted all the layers I am not using and rasterized all the dynamic objects and it's still doing the same thing
Is there any way I can save my file ? I've been working on it for a long time ???
Thanks in advance for any help.

After numerous attempts to rescue the file, I ended up having to recreate it..
I think it was down to a memory bug.. I did empty the clipboard as well during the creation of the file because I was having problems.. maybe it was down to that but I think it actually just became corrupted somehow !
I must admit, it's the first time I've encountered this problem in 15 years of working with photoshop !!
Many thanks for your replies !

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