CAN ANYBODY PLZ HELP: problem opening any program including internet explorer

i recently got rid of "vista internet security 2010". Took me many scans to wipe it and it seems like i finally cleared it. Now i cant click on anything without it popping up a box saying,
"open with: choose the program you want to use to open this file".
I dont understand what happened but it started doing that right after i used my antivirus and it found the trojan.
can anybody plz help me fix this withouth me having to do a complete system restore?
ill greatly appreciate it.

Angie, please be sure to download and run this free tool.
   Malwarebytes' Anti-Malware
"open with: choose the program you want to use to open this file
Which file types (see the "extension" at the end of the file) produce that message?
Which computer? Which Windows?
-Jerry

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