Can I replace my hard drive and then reboot from USB external hard drive

Hi,
I've bought a new internal hard drive to go in my Macbook. I am going to backup my current internal drive to a USB external drive using Super Duper. I just wanted to check if it was at all possible that I would be able to boot up from my external USB drive after i've installed my new internal drive or whether the restore discs were my only option?
(My Macbook is quite an early one, 2Ghz Core Duo with upgraded memory to 2GB and OSX Tiger).
Thanks.

As long as it is a GUID partition table you should be able to boot from it.

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