Can no longer open PDF Files

After running MacKeeper (may be a coincidence), I can nolonger open PDF files. I used to be able to double click and they would open (I think in Preview). Now I get a mesage that I can't open with this version of Mac OS X. Same if I try to open Preview. I am using10.5.8. Can't open with Pages. Can open with Acrobat Reader 5. from within the app.I have restarted my Mac and run software update. How would I redownload Preview or maybe there is another fix??
Need help. Thanks in advance.

Partly great news Stuart, thanks!
No idea how ZeoBit gets away with this slime ware.
There are many good 3ed party Disk/maintenance apps like DiskWarrior, DRive Genius, & maybe even TechTool, but for free...
At this point I think you should get Applejack...
http://www.macupdate.com/info.php/id/15667/applejack
After installing, reboot holding down CMD+s, (+s), then when the DOS like prompt shows, type in...
applejack AUTO
Then let it do all 6 of it's things.
At least it'll eliminate some questions if it doesn't fix it.
The 6 things it does are...
Correct any Disk problems.
Repair Permissions.
Clear out Cache Files.
Repair/check several plist files.
Dump the VM files for a fresh start.
Trash old Log files.
First reboot will be slower, sometimes 2 or 3 restarts will be required for full benefit... my guess is files relying upon other files relying upon other files! :-)
Disconnect the USB cable from any Uninterruptible Power Supply so the system doesn't shut down in the middle of the process.
What happens when you try to use Preview to view PDFs?

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