Can not click buttons or move windows

Hi there,
I have a strange problem. When I click the mouse in certain areas of the screen or within certain windows it does not have any effect. I can move icons around the screen but windows that are recently opened and which sit towards the left centre of the screen seem to be unresponsive to clicks.
Any assistance greatly appreciated.
thanks,
Paula

Try running Firefox in safe-mode.
* Firefox -> Help -> Restart with add-ons disabled
If it works in safe-mode, that means one of your Add-on Extensions is causing the problem, which will require disabling them all, and then re-enabling them one by one to isolate the problem.
Edit:
I forgot to say this earlier, have you checked to see if all plug-ins are up to date?
* http://www.mozilla.org/en-US/plugincheck/

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