Can't get mail to display, quit or open?  Also I can't get photo card drive to work or even shut down the computer because mail won't quit.

Help, I can't get my postage stamp icon to close.  I also can't get a photo card to load or be recognized which I think is due to the mail malfunction.  I tried to restart the computer but it is aborted because mail is still open.  It also won't display or open.  The mail heading is at the top but it doesn't have the quit option in bold.
Any help would be appreciated.

Press   command + option + esc keys on the keyboard together at the same time.
Wait.
Force Quit window will open.
Select Mail, if not already.
Click the "Force Quit" button at the bottom of the window.
Wait. Mail should quit.
If this does not help, press and hold the power button for more than 7 seconds.
Computer will shut down. You may lose the unsaved work.
Best.

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