Can't Open Adobe programs? Help!

I recently replaced my hard drive and still have the old one with all my Adobe applications.
Both hard drives have the same OS and the applications worked on the old one until I replaced it.
I tried to reinstall the Adobe applications and before I can I get the message:
"Adobe Illustrator 13.0.0 [k] (Universal) cannot be opened because of a problem."
without getting the option of installing an update.
I also tried to copy the programs from the Old to the New HD with no luck
Please help, I can't possibly afford to repurchase.

No I did nothing to the old drive but get the case, plug it in and try to use the programs.
Adobe's apps always look for their support files on whatever hard drive contains the currently active operating system. So when you plugged in the external drive and tried to open any of the Adobe apps from it, it looked on the new drive for its support files and didn't find them, and therefore failed to run. This was normal, predictable behavior. Only if you had booted from the old drive would you have had a chance of being able to open the Adobe apps from it.
Put all my other advice on hold for the moment. Connect the old drive to a USB port and start (or restart) the computer, holding down the Option key to bring up the Startup Manager screen. Select the OS on the external drive to start up from, and wait for startup to finish (it will be slower via USB than when the drive is installed internally). Once it's up and running, try to open each of your Adobe apps from it. While doing this, ignore the new internal drive completely — don't open anything on it. If your apps all open, your iTunes library is intact, and nothing else seems to be out of whack, you can proceed to clone the old drive to the new one without swapping them. If all is well on the old disk, all will be well on the new one too.
Looks like great minds think alike at least some of the time.

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