Can't open e-books - message says something about .ascm file

I've installed the program and uninstalled it numerous times and each time I go to open a book I get a message saying that .ascm is not a supported file. Went into defaults and there is no such file listed.  I'm an amateur with all this, so have no idea what to do next.

How are you trying to open them?
I ask because a .pps is a Powerpoint slide show and Adobe REader only opens PDF's.
So, are you double clicking on a file and REader is trying to open them or are you opening Reader then using File>Open and navigating to the file or something else. As many details as you can supply would be good.

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