Can't open Excel files saved to desktop, get popup "There was a problem sending command to the program".

Whenever I save an MS Excel file to my desktop, it creates an icon on the screen. But when I try to open it, I get a popup that says "There was a problem sending the command to the program."
This happens with all Excel files - but MS Word and other files work fine.
Thanks for your help.

Yes, I saw that earlier but it seems to be a temporary fix. I had the same issue return 2 weeks ago, then again yesterday. Each time, I've tried this solution which works but only to see it return at some time in the near future.
Coincidently, I have a similar issue occur on my iPhone 4S w/ iOS 6. There, my keyboard shortcuts won't work in forms unless I tick off Data and Documents iCloud setting, power down the phone, then turn it back on. But like this, it only seems to work for a temporary time and the problem resurfaces in a few days.

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Please mark "Solved" the answer that really solve the problem, to help others with a similar problem.

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When i click on an excel or word file in 2007 the program begins to open but then an error message says There was a problem sending the command to the program

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Hi,
Have you try to un-select the Ignore other applications that use Dynamic Data Exchange (DDE) setting?
Click the Microsoft Office Button, and then click Excel Options.
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If the problem cannot resolve, the Run as administrator may selected.
Go to Office default install location: C:\Program Files\Microsoft Office\Office12.
Right-click EXCEL.EXE > Properties >
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William Zhou
TechNet Community Support

Excel won't open and error message There was a problem sending the command to the programe

Hi there
I'd be grateful for your help.
I've just bought a new laptop and installed Office 2013. I used Excel 2013, did what I needed to do and saved it. This was 5 days ago.
Today, I've tried opening the file from my desktop and get the error message 'There was a problem sending the command to the program'.
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Thanks

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Can't open Excel files saved to desktop, get popup "There was a problem sending command to the program".

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