Can't open Keynote files on my Mac - but they open fine on other Macs

+I had this query in the Keynote 8 section, but was getting no replies - so I'm posting it here too.+
If I attempt to open any Keynote files, I now get this error message.
"Can't open file "+File path: file name+.key"
To clarify, the text in italics above shows the actual file's file path and name.
The file will then will appear on screen, but is unresponsive to any clicks or menu commands.
The files will open successfully on other Macs, so they aren't corrupt.
The same applies when creating a new file from Keynote: All screen menus / buttons are dead - all I can do is drag the main window around the screen.
I've tried to reinstall Keynote, but this hasn't resolved the problem. I've checked that I'm running the latest version (4.04 of Keynote 8) - and I have nearly 12gb free on my hard disc. I've also thrown out any Keynote related files I could find in library or preferences in case some application settings had been corrupted. (Having said that, I don't know if I caught them all - as I just used Spotlight to find files with the name Keynote.)
Are there specific preference / system files that I should look for and dump? Is there an easy way to do a complete uninstall of Keynote so I can try another install? Or is this a symptom of something else?
All ideas gratefully appreciated!

All the issues I describe in my questions around this time re: Keynote were actually symptoms of a soon-to-die laptop. The Hard Disc was corrupting, and Keynote was the first application to be affected.

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