Can't Open Mail Messages

I don't want to use the preview pane in Mail, but I am unable to open mail messages into a new window. If I double click on them nothing happens. Doesn't matter if the preview pane is visible or not. I'm using an iMac Core Duo, running 10.4.6. Any ideas?
iMac Core Duo   Mac OS X (10.4.6)  

No, the preview pane is not necessary to open, double click should do the trick. You can try this:
Open Preferences from within the Mail program and note the exact settings for your email accounts.
Quit Mail
Drag the following file to the desktop:
your home directory / Library / Preferences / com.apple.mail.plist
Restart Mail
Re-install your mail settings for at least one account
These actions will not interfere with your mailboxes, it will simply create a new plist preference file when you re-start Mail.
If that did not help, you can place back the .plist file so you have all your account settings back.

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