Can't open most applications

When I try to open most applications from dock or applications folder nothing will open. Acts as if application is already open (but its not!) Can't open Safari, mail itunes, imovie etc. only iDVD will open.
When it try it thru the dock the icon bounces up once and thats it no opening!

HI,
When you can run Disk Utility from your install disc...
Insert your install disk and Restart, holding down the "C" key until grey Apple appears.
Go to Installer menu and launch Disk Utility.
(In Mac OS X 10.4 or later, you must select your language first from the installer menu)
Select your HDD (manufacturer ID) in the left panel.
Select First Aid in the Main panel.
(Check S.M.A.R.T Status of HDD at the bottom of right panel. It should say: Verified)
Click Repair Disk on the bottom right.
If DU reports disk does not need repairs quit DU and restart.
If DU reports errors Repair again and again until DU reports disk is repaired.
When you are finished with DU, from the Menu Bar, select Utilities/Startup Manager.
Select your start up disk and click Restart
While you have the Disk Utility window open, look at the bottom of the window. Where you see Capacity and Available. Make sure there is always 10% to 15% free disk space
Carolyn

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