Can't open PDFs in any viewer but Quicklook works

All of a sudden I can't open PDFs in Acrobat, Preview or PDF Pen. They display fine in Quicklook, though. I can't recall anything that changed that would cause this. Ideas?

Highlight your file>File>Get Info>
In the Get Info window, scroll down to "Open with:"
Unselect the "Change All..." button if you want to "Use this application to open all documents like this.”

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