Can't quit Safari

Several times now, when I choose to end a session in Safari, neither 'CMD+Q' or 'Safari>Quit' Safari work. In fact, the 'Quit Safari' option is greyed out and choosing 'Quit' from the dock yields no response.
Logging out doesn't work, nor does shutting down, as Safari cancels logout. All that works is a 'Force Quit' but of course, that doesn't solve the problem.
I have seen from other forums, both on this site and elsewhere, that this is a common and well-known problem, and has been for some time, so I assume Apple is aware of it. If they are, I must say I'm dismayed by the lack of support.
Sorry if I'm coming off as cranky here, but it's rather frustrating and I'm this close to abandoning my beloved Safari for another browser.
Does anyone have a real solution to this problem? Or know of a way I can find one?
Thank you in advance.

90% of the time only one account is affected. Create a test account or use the Guest account.
If you can establish that it is only one account you could remove all Safari files from that account as follows:
First export bookmarks then quit Safari.
Open Terminal - in Utilities and paste all the commands below - make sure it is the same as here - particularly first and last characters - then hit return - it will save your Safari folder with a date stamp on your Desktop and delete several files. Start safari, reset preferences and import bookmarks.
mv ~/Library/Safari ~/Desktop/Safari-`date +%Y%m%d%H%M%S`; \
rm -Rf ~/Library/Caches/Apple\ -\ Safari\ -\ Safari\ Extensions\ Gallery; \
rm -Rf ~/Library/Caches/Metadata/Safari; \
rm -Rf ~/Library/Caches/com.apple.Safari; \
rm -Rf ~/Library/Caches/com.apple.WebKit.PluginProcess; \
rm -Rf ~/Library/Cookies; \
rm -Rf ~/Library/Preferences/Apple\ -\ Safari\ -\ Safari\ Extensions\ Gallery; \
rm -Rf ~/Library/Preferences/com.apple.Safari.LSSharedFileList.plist; \
rm -Rf ~/Library/Preferences/com.apple.Safari.RSS.plist; \
rm -Rf ~/Library/Preferences/com.apple.Safari.plist; \
rm -Rf ~/Library/Preferences/com.apple.WebFoundation.plist; \
rm -Rf ~/Library/Preferences/com.apple.WebKit.PluginHost.plist; \
rm -Rf ~/Library/Preferences/com.apple.WebKit.PluginProcess.plist; \
rm -Rf ~/Library/PubSub/Database; \
rm -Rf ~/Library/Saved\ Application\ State/com.apple.Safari.savedState 

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