Can't send mail after 10.5.6

Anyone having trouble sending email after upgrading? I can receive it fine, but sending has been a no-go for nearly 24 hours now. All my server settings are accurate and my ISP reporst no issues on their end.
What gives?

I've been having this problem for weeks, and many other have too, if you go back through the forum. In my case I'm using a Sprint mobile broadband modem (Sierra Compass 597) on my MacBook Pro. I can receive but not send - but erratically. Sometime is works just fine. I've done all the troubleshooting and had long conversations with the support people at my isp. Works for awhile, but then deteriorates.
But I CAN ALWAYS send over my old dial-up land line modem!
And as for the Sprint modem - it works just fine on my wife's PC to the same isp.
She's considering replacing it with a Mac, but not until I solve this issue!
Every day I check for a software update - but in vain. I even took it to the Geniuses at my local Apple store and they were stumped.

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i cant use mail to send an email. it goes to my out box and then eventually comes up with this dialogue :
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From the Mail menu bar, select
Window ▹ Connection Doctor
Click the Show Detail button. A drawer opens. Try to send a message and post the text that appears. Anonymize any personal information before posting.

Can't "Send" mail after last Security Update

Installed the download two days ago.
Incoming mail is fine.
Nothing to do with smpt server.
"New message" or "reply" window has "send" button shaded out.
Dropdown menu "send" is gray ... can't use.

Was this for 10.5.8???
Others have reported it for 10.6.8 & up...
http://x704.net/bbs/viewtopic.php?f=12&t=6118

TS1307 can't send mail after file sharing using bluetooth

I treid to set up file sharing between my macbook pro and my husband's macbook and this has effected Mail. He can receive email but not send from his laptop but can do so remotely. Some thing has changed on his laptop but I can't find out what. Any help?

Make a New Location, Using network locations in Mac OS X ...
http://support.apple.com/kb/HT2712
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System Preferences>Network, top of window>Locations>Edit Locations, little plus icon, give it a name.
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The error message says:
"The sender address [my email address] was rejected by the server smtp.east.cox.net.
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There is only one server I can use. There is a button for the Connection Doctor, and that shows all green lights.

Can't send mail after security update

Hello, I installed a security update friday night, and can no longer send email using either Mail 2.1 or Thunderbird. Both were working prior to the security update.
I am not getting any error messages except for the ones over the phone that go..."did you get my email? What email?" In fact, both Mail and Thunderbird give every indication that the email was sent.
I can mail myself a test from a web program, so my smtp server is working.
I can receive mail fine.
I am blaming the security update for this, but I have no idea where to look or what to do. Can I uninstall the update?

You're welcome.
The thing is, AFAIK Mail wouldn't put the message in the Sent mailbox unless it has received confirmation from the outgoing server that the message has indeed been sent, so it seems to me that the problem is not that messages are not being sent, but rather that they don't arrive at the destination for some reason.
I bcc myself on every email for filing reasons and have
not recieved one of my own emails since Friday night.
Do you receive other mail normally? Have you checked for those messages on the web?
I can log into my employers web tool and send email that way,
so something is going on with my machine, whatever it is.
Well, not necessarily. Maybe there is something wrong with the outgoing server you're using in Mail. Is this your only mail account? Do you have access to any other outgoing server that you could try?

Can't send mail after 10.5.6

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