Can't send mail error 550 and 554--unrecognized user or relay denied

I've done a clean install of server 10.4.11. When I try to send mail from my mobile me account tot he server I am getting one of two different errors: 550 unknown user, or 554 relay access denied. I'm dog tired after an all-nighter and not thinking clearly.
Here is my postconf -n output:
command_directory = /usr/sbin
config_directory = /etc/postfix
daemon_directory = /usr/libexec/postfix
debugpeerlevel = 2
enableserveroptions = yes
html_directory = no
inet_interfaces = all
mail_owner = postfix
mailboxsizelimit = 0
mailbox_transport = cyrus
mailq_path = /usr/bin/mailq
manpage_directory = /usr/share/man
mydestination = $myhostname,localhost.$mydomain,localhost,mail.trinidadchroniclenews.com,trinid adchroniclenews.com
mydomain = mail.trinidadchroniclenews.com
mydomain_fallback = localhost
myhostname = mail.trinidadchroniclenews.com
mynetworks = 127.0.0.0/8
mynetworks_style = host
newaliases_path = /usr/bin/newaliases
queue_directory = /private/var/spool/postfix
readme_directory = /usr/share/doc/postfix
sample_directory = /usr/share/doc/postfix/examples
sendmail_path = /usr/sbin/sendmail
setgid_group = postdrop
smtpdclientrestrictions = permitsaslauthenticated, permit_mynetworks, rejectrblclient sbl-xbl.spamhaus.org rejectrblclient list.dsbl.org rejectrblclient bl.spamcop.net permit
smtpdpw_server_securityoptions = login
smtpdrecipientrestrictions = permitsasl_authenticated,permit_mynetworks,reject_unauthdestination,permit
smtpdsasl_authenable = yes
smtpdtls_keyfile =
smtpduse_pwserver = yes
unknownlocal_recipient_rejectcode = 550
TIA
Rob

The MX record for trinidadchroniclenews.com points to mail.trinidadchroniclenews.com which.
Telnetting to this host on port 25 I get:
220 orionwebhost.com ESMTP Exim 4.62 Fri, 28 Aug 2009 09:03:54 -0700
Since Mac OS X Server runs Postfix and not Exim, either your DNS records are wrong or your ISP is intercepting port 25.
HTH,
Alex

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