Can't start CS5 64-bit in Windows 7

Can't seem to find an exact fix for this problem. I reinstalled Windows 7 (64-bit version), and of course had to reinstall all applications. Verified I'm running Win7-64 bit, but now when I launch Photoshop CS5-64 bit, I only get an error message that says "System unable to find file specified", even though the file is listed in the proper place by Explorer. I'm able to launch CS5-32 bit version normally, but of course that version limits the RAM available to about 3GB and I have 16GB installed. I'm able to successfully launch Lightroom 3 in 64-bit mode.
I've tried uninstalling Photoshop CS5, rebooting and re-installing in a different location with a fresh download of CS5 from Adobe.com but still always the same error message that "System cannot find file specified" when launching.
Any ideas on how to fix this?

Many thanks.
I think you've got two different types of problem going on at once here. Let's try clearing this second error out of the way first.
the second is "Error writing to file: C:\ Program Files(x86)\Common Files\Apple\Apple Application Support\Webkit.resources\inspector\Images\timelinePillGreen.png. Verify that you still have acess to that directory."
That one's consistent with disk/file damage. The first thing I'd try with that is running a disk check (chkdsk) over your C drive.
XP instructions in the following document: How to perform disk error checking in Windows XP
Vista instructions in the following document: Check your hard disk for errors
Windows 7 instructions in the following document: How to use CHKDSK (Check Disk)
Select both Automatically fix file system errors and Scan for and attempt recovery of bad sectors, or use chkdsk /r (depending on which way you decide to go about doing this). You'll almost certainly have to schedule the chkdsk to run on startup. The scan should take quite a while ... if it quits after a few minutes or seconds, something's interfering with the scan.
Does the chkdsk find/repair any damage? If so, can you get an install to go through without that particular error message afterwards? (Whether this works or not, we still might have to deal with the system services message.)

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