Can't sync iPhone with iTunes on Mac book pro.

I have a iPhone 4 that I just now updated to version 5.1.  I have a Macbook Pro running Mac OS X version 10.6.8.
When I connect my phone to the computer w the USB cable, nothing happens.  iTunes does not "see" the phone.
I also have wifi and when I try to sync using this, I get a message on the phone "Sync will resume when"Macintosh.local" is available."
I have done a sync before with no problem using the cable.  I have restarted both the phone and the computer.  What am I doing wrong now?

I have tried all the suggestions on the support site Mr. Finch suggested.  I have removed iTunes and after the third try, have downloaded and reinstalled iTurns.  Still no sync.  I have rebooted the router, computer, iPhone and still no sync.
It worked fine a month ago. Yesterday the sync worked fine on my other macbook pro to sync File Maker Pro.
Any suggestions?

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