Can't update iPod, "required file is in use."

Whenever I connect my iPod to either my work computer (a PowerMac G4) or my laptop (a PowerBook G4) I get an alert message in iTunes that reads, 'The iPod "Thomas's iPod Mini" could not be updated. The required file is in use.' This message sometimes pops up every few minutes and is VERY annoying. FYI, I have my iTunes Library on an external USB hard disk, but I don't think that has anything to do with it.
Does anyone know what is going on?
PowerBook G4 1Ghz   Mac OS X (10.4.8)   iPod Mini 4Gb

I think I solved it (my mac inf. below):
I opened preferences in Norton AntiVirus v.10.1.1(003) and went to Auto Protect "Safe Zones" added my iPod to the "Everywhere EXCEPT in:" field from the mounted volumes area and alls well so far even with auto protect enabled.
I don't even get the problem on ejecting the iPod from iTunes anymore ('can't eject because iPod is in use by another program').
hope this helps.
(anyone got a suggestion on how I can quiet down my mac's windtunnel like cooling fans?)
my mac inf.:
Machine Name: Power Mac G4
Machine Model: PowerMac3,6
CPU Type: PowerPC G4 (3.3)
Number Of CPUs: 2
CPU Speed: 1.42 GHz
L2 Cache (per CPU): 256 KB
L3 Cache (per CPU): 2 MB
Memory: 1 GB
Bus Speed: 167 MHz
Boot ROM Version: 4.6.0f1
Powermac G4 (windtunnel)   Mac OS X (10.4.8)   my mac's fans are too loud!

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