Cannot get itunes to run on xp.  Every time i download, it finishes installation then can't open because files are missing

I can't get itunes to download and actually work on my PC.  I have quicktime downloaded and functioning, have updated everything several times, uninstalled and reinstalled from different links...when it completes the installation phase,  I get a congrats screen, then it refuses to load because files are missing. 
Sometimes, on startup, Itunes suddenly opens, although the shortcut still wont work.  It sees my Ipod (new, latest generation) sees my songs, attempts to sync then I get a 1450 error and the whole thing closes, not to be opened again until the next time I reboot and it occurs. 
Anyone help?  I've turned off my firewall, filters, pop up blockers, everything I can think of.  Been at this a month now....

Troubleshooting issues with iTunes for Windows updates - MSVCR80

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