Cannot get itunes to work please help

When I double clik on ITunes it takes ages to start then when i plug my ipod or shuffle in the window opens showing the drive ie. E:\ for my shuffle and i get the following message in itunes " The software required for communicating with the Ipod s not installed correctly. Please re-install ITunes to re-installthe Ipods software"
I have uninstalled and re-installed, clean out the registry tried selective startup.
Been without itunes for over a week now any help would be much appreciated.
I also installed Itunes on my works laptop and this operates fine and sees the ipods, all be it without my library.

this is what i get when i run diagnostics in itunes with shuffle connected
Microsoft Windows XP Home Edition Service Pack 2 (Build 2600)
Gericom Ego
iTunes 7.7.0.43
QuickTime 7.5
CD Driver 2.0.7.3
CD Driver DLL 2.1.1.1
Apple Mobile Device 2.0.0.33
Bonjour 1.0.4.12 (118.4)
iTunes Serial Number 00C44CCC186A10D9
Current user is an administrator.
The current local date and time is 2008-07-30 10:56:04.
iTunes is not running in safe mode.
Video Display Information
ATI MOBILITY RADEON 9700
** External Plug-ins Information **
No external plug-ins installed.
** iPod/iPhone Connectivity Tests **
iPodService 7.7.0.43 is currently running.
iTunesHelper is currently not running.
Apple Mobile Device service 2.0.28.0 is currently running.
Universal Serial Bus Controllers:
Intel(R) 82801DB/DBM USB Universal Host Controller - 24C2 . Device is working properly.
Intel(R) 82801DB/DBM USB Universal Host Controller - 24C4 . Device is working properly.
Intel(R) 82801DB/DBM USB Universal Host Controller - 24C7 . Device is working properly.
Intel(R) 82801DB/DBM USB2 Enhanced Host Controller - 24CD . Device is working properly.
FireWire (IEEE 1394) Host Controllers:
OHCI Compliant IEEE 1394 Host Controller. Device is working properly.
Most Recent Device Not Currently Connected:
iPod shuffle (2nd & 3rd Generation) running firmware version 1.0.4
Serial Number: 5E643ZULVTE

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