Cannot hear itunes or video on iPhone4s

My iPhone4s just updated itself yesterday and I don't have any sound for my music or videos. The speaker works for phone calls, SIRI and voicemail.  The phone is unmuted. My phone is only 2 weeks old!

Hello, tombngs. 
Thank you for visiting Apple Support Communities. 
Here are the steps that I would recommend going through for error 3221. 
iTunes for Windows: -3221 error displays when accessing iTunes Store
http://support.apple.com/kb/TS1485
Cheers,
Jason H. 

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