Cannot launch Lightroom

Message box with the following message: 
Lightroom
[Main Instruction]
Lightroom encountered an error when reading from its preview cache and needs to quit.
[Content]
Lightroom will attempt to fix this problem the next time it launches.
[OK]
Upon attempting to relaunch Lightroom I get the same message repeatedly.  Will not launch.

http://forums.adobe.com/message/6315616?tstart=0#6315616

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