Cannot Left Click anything in AE

This happened today, everything has been working just fine, but now when I start Adobe After Effects CS4 (or CS5) either or, I can left click New Composition, but when the menu opens up to select 1280x720 etc, I cannot left click on anything, as I roll the cursor over the boxes, it DOES highlight as if I could select it, but clicking does absolutely nothing. I can TAB through the selections and work that way, but obviously that is a pain in the *&*^.
I can click on CLOSE (the red X) and close After effects, I can click and select any of the top menu itesms (File, Edit, Composition, Layer, etc) just fine, even when I go into preferences, I cannot select anything with the mouse.
I am using windows 7 Ultimate 64x, all current updates, 16gb of ram, quad core cpu, 2x5970, and NO its not the mouse, it works fine in every single other app.
When I open AE CS4, the cursor cannot select, as well as it looks like a pixelated waffle, like a square of black and white pilxels.
I have tried rebooting, and taken out all plugins.
Please I need help! thanks!

Ahh, this *might* be it, I did turn on dual monitors yesterday, so can I not run dual monitors with After Effects? I didn't update my video drivers, maybe I should? Let me turn off the second monitor and see if that corrects the issue. brb.
Ok that worked!!! for CS5, it's working like perfect. So can I not run dual monitors? That would be a real pain!
CS4 still has the pixelated "waffle" corruption cursor. The graphics cards are not overclocked and the CPU and GPU are below average temps.
Thats a pic of what it looks like..
Thanks for helping

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iMac 20 inch core 2 due,Macbook pro 2.33 core 2 due 17" Mac OS X (10.4.8) apple cinema display 20"
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Yes i did.
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OK the amount I hate myself right now is more than a fat guy's self loathing for raiding the fridge at 2am for Pizza but less than an armed robber who's accidentally shot a pregnant woman in the stomach during a shootout. but not much less.
So after I had miraculously got the Flash Player Setting Panel to work again, (after deleting QuickTime and leaving the window open for abut an hour it just started working again) I then got enticed into downloading the ustream producer software.
While downloading it informed me that it would only work with QuickTime.
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What did I do? I fixed it and f***ing broke it again!
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Help forum PLEASE!
Regards,
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Cannot Left Click anything in AE

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