Cannot Open Acrobat Reader

I have Reader version 8.1.2, which I use on Windows XP Pro. Most of the time when I try to open a download I get the message "Error Opening this document. This file cannot be found".
This is so frustrating because I have to look at lots of PDF files. Occasionally it opens, but reverts to the error message on the subsequent times.
Does anybody have a solution for this.

Thank you for that tip. When I download attachments from an email and it does that error, I can retrieve the downloaded PDF by going into My Documents. The problem comes when I am obtaining quotes or other information directly from a website, because they are not saved anywhere. If I could open them, I could then save them or print them off, but in this case I cannot even see them.

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