Cannot Open Any PSD Files Without Beachballing

Photoshop is going non-responsive any time I try to open a file.  If I try to open a PSD in Ai it does the same thing. I'm currently at a standstill.  I'm running Photoshop CS4 11.0 and running it on OS X Version 10.6.1, 2.8GHz Core 2 Duo, 4 GB 1067 MHz DDR3 MacBook Pro. 

http://forums.adobe.com/thread/370735?tstart=0
But I think a new user would start with fresh prefs anyway, so that may not make any further difference …

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