Cannot Open File error - tried what I know

I have received the dreaded Cannot Open File error. Usually I can manage to recover the file by deleting the lock file or recovering from a backup. This time, nothing is working.
I've searched the forum, and while many people have this issue I cannot find a solution.
Any suggestions?
Thanks!

Hi,
Have you checked this article for steps to recover a project from Cache. (Adobe Captivate Cache Projects folder from My Documents)
http://blogs.adobe.com/captivate/2010/09/recovering-the-project.html
For Future, make sure you have the option to create project Backup on save automatically at the same location where your project is saved. (Edit--Preferences--General-- Generate Project backup)
Thanks,
Anjaneai

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