Cannot open Itunes in Vista.

I have tried all the fixes and nothing works.  Itunes does not open in Vista.  Also, Cannot open itunes in safe mode.

Many thanks.
Can you check something for me please?
Restart your PC. after the PC restarts, bring up your Task manager, and go to the "Processes" tab. Click "Image name" to sort the processes alphabetically.
Now try to launch iTunes.
Does an itunes.exe process appear? If so, does it vanish after a second or so, or does it persist in the Processes tab (even though iTunes itself never shows up)?

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    Apple Mobile Device Support (if this won't uninstall move on to the next item)
    Bonjour
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    Reboot, download iTunes, then reinstall, either using an account with administrative rights, or right-clicking the downloaded installer and selecting Run as Administrator.
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    HT1925: Removing and Reinstalling iTunes for Windows XP
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    If anyone is reading this still looking for what caused the issue and how to fix it here is what I discovered.
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