Cannot open mailbox system attendand- randomly

Hello,
our environment have Exchange 2013 with CU7 installed, and lately receive weird problem that is not persistent but it unexplained.
All databases mounted that are in DAG, all arbitration mailboxes good, in ADSIEDIT checked homeMDB, and it is not set, however, i dont know is this relevant because sometimes is failing, sometimes is success.
When we run user creation we randomly get error:
Cannot open mailbox /o=ORGANIZATION/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Configuration/cn=Servers/cn=SERVER/cn=Microsoft System Attendant. CategoryInfo: NotSpecified: (:) [Set-MailboxRegionalConfiguration],
MailboxUnavailableException, FullyQualifiedErrorId: [Server=SERVER,RequestId=ba479b62-bda0-4c55-9347-9279f6121d62,TimeStamp=3/18/2015 7:57:29 PM] [FailureCategory=Cmdlet-MailboxUnavailableException] 45AC6FDA,Microsoft.Exchange.Management.StoreTasks.SetMailboxRegionalConfiguration
Googled many answers, tried many workarounds, and I'm out of ideas now, so any suggestion will be more than welcome!
Thanks,
Ivica

Well, i would do that, except that Exchange 2013 don't have System attendant service.
Also, we have 6 databases, how do i know which one to put in homeMDB field?
I did as you instructed anyway for test and still receive error:
<?xml version="1.0"?>
<Objects>
  <Object Type="System.Management.Automation.PSCustomObject">
    <Property Name="message" Type="System.String">Can't create user</Property>
    <Property Name="detailMessage" Type="System.String">Cannot open mailbox /o=secureemail/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Configuration/cn=Servers/cn=SERVER/cn=Microsoft System Attendant. CategoryInfo:
NotSpecified: (:) [Set-MailboxRegionalConfiguration], StorageTransientException, FullyQualifiedErrorId: [Server=SERVER,RequestId=557e3eb8-ddbb-44c9aab1-d18c0682beb5,TimeStamp=3/19/2015 2:45:32 PM] [FailureCategory=Cmdlet-StorageTransientException] 2CC71ED6,Microsoft.Excha
nge.Management.StoreTasks.SetMailboxRegionalConfiguration</Property>
    <Property Name="responseCode" Type="System.String">400</Property>
  </Object>
</Objects>
Keep in mind that servers are in remote AD sites, replication and AD health is good!
This is script that is failing:
$ErrorActionPreference = "Stop";
try{
Add-PSSnapin Microsoft.Exchange.Management.PowerShell.SnapIn
$OrganizationName = "[email protected]" #User defined mail address
$organizationUnit = "OU=$OrganizationName,OU=users,DC=domain,DC=priv";
$name = "John"                                            
#this should be asked in web interface (firstname)
$lastname = "Dpe"                                              
#this should be asked in web interface (lastname)
$displayName = "John Doe" # this is display name in OWA and in all address books
$logonName = "john"    # this will be users choosen logon name (before @externaldomain.com)
$ExternalDomain = "example.com"        #this value user will enter as his wanted username and will use it together with his external domain name [email protected]
$UPN = "$LogonName@$ExternalDomain"   #this should remain to be done automatically and under assumption domain is provisioned!!
$DomainController = "server"   #this value must be specified based on domain controller in AD site where user will be created
$nonadmin = "$OrganizationName All Users"; #This is field for entire tenant management and members are used for calendar sharing
$database = "database"                               
$retentionPolicy = "DoNotRemove"
$customattribute1 = "$OrganizationName" #Add for possible manipulation of tenants for future need
$customattribute2 = "ServiceID"
$customattribute3 = "ContactID"
$customattribute4 = "ClientID"
$password =ConvertTo-SecureString 'Password123' -AsPlainText -Force
$mailbox = New-Mailbox -DomainController "$DomainController" -RetentionPolicy $retentionPolicy -UserPrincipalName $UPN -Name "$name $lastname" -OrganizationalUnit "$organizationUnit" -Password $password -FirstName "$name"
-LastName "$lastname" -Displayname "$Displayname" -database $database -ResetPasswordOnNextLogon $false  #This is part where user is created
Start-Sleep -s 2;
Add-DistributionGroupMember -Identity "$nonadmin" -Member "$UPN" -BypassSecurityGroupManagerCheck  -DomainController "$DomainController"      #at this line user is placed in distribution group and
that group is used for additional security
Start-Sleep -s 2;
Set-Mailbox -AddressBookPolicy "$OrganizationName ABP" -Identity "$UPN" -DomainController "$DomainController" #from this point user gets his address book and isolation part.
Set-Mailbox -Identity "$UPN" -DomainController "$DomainController" -EmailAddressPolicyEnabled:$False #disables force of address policy
Set-Mailbox -identity "$UPN" -PrimarySmtpAddress  $UPN  -DomainController "$DomainController" ; #assigns default mail address
Start-Sleep -s 2;
Set-CASMailbox -identity "$UPN" -OwaMailboxPolicy Default  -DomainController "$DomainController" #In this policy it is defined that user cant manage his password, as any future change will be managed globally here and automatically
applied to all users
Set-MailboxRegionalConfiguration -Identity "$UPN" -Language en-us -DomainController "$DomainController" -Confirm:$False
Set-MailboxFolderPermission -identity ${UPN}:\calendar -User default -accessrights none -DomainController "$DomainController"   
add-MailboxFolderPermission -Identity ${UPN}:\calendar -user "$nonadmin" -AccessRights AvailabilityOnly -DomainController "$DomainController"    #only members of classic users can see free/busy
set-mailbox -identity $UPN -customattribute1 $customattribute1 -customattribute2 $customattribute2 -customattribute3 $customattribute3 -customattribute4 $customattribute4 -DomainController "$DomainController"
$mailbox | Set-CasMailbox -DomainController "$DomainController" -ActiveSyncEnabled $true -PopEnabled $true -ImapEnabled $true -OWAEnabled $true -MAPIEnabled $true; #adding script for created user to be returned after creation

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        <TimeCreated SystemTime="2011-11-07T03:41:35.000000000Z" />
        <EventRecordID>90607</EventRecordID>
        <Channel>Application</Channel>
        <Computer>www.myservername.com</Computer>
        <Security />
      </System>
      <EventData>
        <Data>Subject: myservername.com/Users/Administrator : Mount-Database
    Body:
    Cmdlet Name: Mount-Database
    Object Modified: Mailbox Database 2034345905
    Parameter: Identity = Mailbox Database 2034345905
    Caller: myservername.com/Users/Administrator
    Succeeded: False
    Error: System.InvalidOperationException: Couldn\'t mount the database that you specified. Specified database: Mailbox Database 2034345905; Error code: An Active Manager operation failed. Error: The database action failed. Error: Operation failed with message:
    MapiExceptionCallFailed: Unable to mount database. (hr=0x80004005, ec=-583)\n. [Database: Mailbox Database 2034345905, Server: WWW.myservername.com]. ---&gt; Microsoft.Exchange.Cluster.Replay.AmDbActionWrapperException: An Active Manager operation failed.
    Error: The database action failed. Error: Operation failed with message: MapiExceptionCallFailed: Unable to mount database. (hr=0x80004005, ec=-583)\n. ---&gt; Microsoft.Exchange.Data.Storage.AmOperationFailedException: An Active Manager operation failed.
    Error: Operation failed with message: MapiExceptionCallFailed: Unable to mount database. (hr=0x80004005, ec=-583)\n. ---&gt; Microsoft.Mapi.MapiExceptionCallFailed: MapiExceptionCallFailed: Unable to mount database. (hr=0x80004005, ec=-583)\n\r\n  
    at Microsoft.Mapi.MapiExceptionHelper.ThrowIfError(String message, Int32 hresult, SafeExInterfaceHandle iUnknown, Exception innerException)\r\n   at Microsoft.Mapi.ExRpcAdmin.MountDatabase(Guid guidStorageGroup, Guid guidMdb, Int32 ulFlags)\r\n  
    at Microsoft.Exchange.Cluster.ActiveManagerServer.AmStoreHelper.Mount(Guid mdbGuid, MountFlags flags)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.ActiveManagerCore.&lt;&gt;c__DisplayClassb.&lt;MountDatabaseDirect&gt;b__2()\r\n  
    at Microsoft.Exchange.Cluster.Replay.FailoverPerformanceTrackerBase`1.RunTimedOperation(TOpCode opCode, Action operation)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.ActiveManagerCore.MountDatabaseDirect(Guid mdbGuid, MountFlags storeFlags,
    AmMountFlags amMountFlags, AmDbActionCode actionCode)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.AmRpcServer.&lt;&gt;c__DisplayClass19.&lt;MountDatabaseDirect&gt;b__18()\r\n   at Microsoft.Exchange.Data.Storage.Cluster.HaRpcExceptionWrapperBase`2.RunRpcServerOperation(String
    databaseName, RpcServerOperation rpcOperation)\r\n   --- End of inner exception stack trace (Microsoft.Mapi.MapiExceptionCallFailed) ---\r\n   --- End of stack trace on server (www.myservername.com) ---\r\n   at Microsoft.Exchange.Data.Storage.Cluster.HaRpcExceptionWrapperBase`2.ClientRethrowIfFailed(String
    databaseName, String serverName, RpcErrorExceptionInfo errorInfo)\r\n   at Microsoft.Exchange.Data.Storage.ActiveManager.AmRpcClientHelper.RunRpcOperationWithAuth(AmRpcOperationHint rpcOperationHint, String serverName, String databaseName, NetworkCredential
    networkCredential, Nullable`1 timeoutMs, InternalRpcOperation rpcOperation)\r\n   at Microsoft.Exchange.Data.Storage.ActiveManager.AmRpcClientHelper.MountDatabaseDirectEx(String serverToRpc, Guid dbGuid, AmMountArg mountArg)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.AmDbAction.MountDatabaseDirect(AmServerName
    serverName, AmServerName lastMountedServerName, Guid dbGuid, MountFlags storeFlags, AmMountFlags amFlags, AmDbActionCode actionCode)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.AmDbStandaloneAction.&lt;&gt;c__DisplayClass2.&lt;MountInternal&gt;b__0(Object
    , EventArgs )\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.AmHelper.HandleKnownExceptions(EventHandler ev)\r\n   --- End of inner exception stack trace (Microsoft.Exchange.Data.Storage.AmOperationFailedException) ---\r\n  
    at Microsoft.Exchange.Cluster.ActiveManagerServer.AmDbOperation.Wait(TimeSpan timeout)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.ActiveManagerCore.MountDatabase(Guid mdbGuid, MountFlags storeFlags, AmMountFlags amMountFlags, DatabaseMountDialOverride
    mountDialOverride, AmDbActionCode actionCode)\r\n   at Microsoft.Exchange.Cluster.ActiveManagerServer.AmRpcServer.&lt;&gt;c__DisplayClass4.&lt;MountDatabase&gt;b__3()\r\n   at Microsoft.Exchange.Data.Storage.Cluster.HaRpcExceptionWrapperBase`2.RunRpcServerOperation(String
    databaseName, RpcServerOperation rpcOperation)\r\n   --- End of stack trace on server (WWW.myservername.com) ---\r\n   at Microsoft.Exchange.Data.Storage.Cluster.HaRpcExceptionWrapperBase`2.ClientRethrowIfFailed(String databaseName, String
    serverName, RpcErrorExceptionInfo errorInfo)\r\n   at Microsoft.Exchange.Data.Storage.ActiveManager.AmRpcClientHelper.RunDatabaseRpcWithReferral(AmRpcOperationHint rpcOperationHint, Database database, String targetServer, InternalRpcOperation rpcOperation)\r\n  
    at Microsoft.Exchange.Management.SystemConfigurationTasks.MountDatabase.RequestMount(MountFlags storeMountFlags)\r\n   at Microsoft.Exchange.Management.SystemConfigurationTasks.MountDatabase.InternalProcessRecord()\r\n   --- End of inner
    exception stack trace ---
    Run Date: 2011-11-07T03:41:32
    OriginatingServer: WWW (14.01.0355.001)
    </Data>
        <Data>
        </Data>
        <Data>Microsoft.Exchange.Data.Storage.ConnectionFailedTransientException: Cannot open mailbox /o=myservername/ou=Exchange Administrative Group (FYDIBOHF23SPDLT)/cn=Configuration/cn=Servers/cn=WWW/cn=Microsoft System Attendant. ---&gt;
    Microsoft.Mapi.MapiExceptionNetworkError: MapiExceptionNetworkError: Unable to make connection to the server. (hr=0x80040115, ec=-2147221227)
    Diagnostic context:
        Lid: 13720   dwParam: 0x6D9      Msg: EEInfo: Flags: 0
        Lid: 11672   dwParam: 0x6D9      Msg: EEInfo: NumberOfParameters: 4
        Lid: 8856    dwParam: 0x6D9      Msg: EEInfo: prm[0]: Unicode string: ncacn_ip_tcp
        Lid: 8856    dwParam: 0x6D9      Msg: EEInfo: prm[1]: Unicode string: WWW.myservername.com
        Lid: 12952   dwParam: 0x6D9      Msg: EEInfo: prm[2]: Long val: -545057711
        Lid: 12952   dwParam: 0x6D9      Msg: EEInfo: prm[3]: Long val: 382312662
        Lid: 45169   StoreEc: 0x824    
        Lid: 44273 
        Lid: 59431   EMSMDB.EcDoConnectEx called [length=177]
        Lid: 34855   EMSMDB.EcDoConnectEx returned [ec=0x0][length=82][latency=31]
        Lid: 25964   StoreEc: 0x824    
        Lid: 38951   EMSMDB.EcDoDisconnect called [length=8]
        Lid: 55335   EMSMDB.EcDoDisconnect returned [ec=0x0][length=12][latency=0]
        Lid: 36081 
        Lid: 52465   StoreEc: 0x80040115
        Lid: 60065 
        Lid: 33777   StoreEc: 0x80040115
        Lid: 59805 
        Lid: 52209   StoreEc: 0x80040115
        Lid: 56583 
        Lid: 52487   StoreEc: 0x80040115
        Lid: 19778 
        Lid: 27970   StoreEc: 0x80040115
        Lid: 17730 
        Lid: 25922   StoreEc: 0x80040115
       at Microsoft.Mapi.MapiExceptionHelper.ThrowIfError(String message, Int32 hresult, SafeExInterfaceHandle iUnknown, Exception innerException)
       at Microsoft.Mapi.ExRpcConnection.Create(ConnectionCache connectionCache, ExRpcConnectionCreateFlag createFlags, ConnectFlag connectFlags, String serverDn, String userDn, String user, String domain, String password, String httpProxyServerName,
    Int32 ulConMod, Int32 lcidString, Int32 lcidSort, Int32 cpid, Int32 cReconnectIntervalInMins, Int32 cbRpcBufferSize, Int32 cbAuxBufferSize, Client xropClient, Byte[] clientSessionInfo, TimeSpan connectionTimeout)
       at Microsoft.Mapi.MapiStore.OpenMapiStore(String serverDn, String userDn, String mailboxDn, Guid guidMailbox, Guid guidMdb, String userName, String domainName, String password, String httpProxyServerName, ConnectFlag connectFlags, OpenStoreFlag
    storeFlags, CultureInfo cultureInfo, Boolean wantRedirect, String&amp; correctServerDN, ClientIdentityInfo clientIdentity, String applicationId, Client xropClient, Boolean wantWebServices, Byte[] clientSessionInfo, TimeSpan connectionTimeout)
       at Microsoft.Mapi.MapiStore.OpenMailbox(String serverDn, String userDn, String mailboxDn, String userName, String domainName, String password, ConnectFlag connectFlags, OpenStoreFlag storeFlags, CultureInfo cultureInfo, WindowsIdentity windowsIdentity,
    String applicationId)
       at Microsoft.Exchange.Data.Storage.MailboxSession.ForceOpen(MapiStore linkedStore)
       --- End of inner exception stack trace ---
       at Microsoft.Exchange.Data.Storage.MailboxSession.ForceOpen(MapiStore linkedStore)
       at Microsoft.Exchange.Data.Storage.MailboxSession.Initialize(MapiStore linkedStore, LogonType logonType, ExchangePrincipal owner, DelegateLogonUser delegateUser, Object identity, OpenMailboxSessionFlags flags, GenericIdentity auxiliaryIdentity)
       at Microsoft.Exchange.Data.Storage.MailboxSession.&lt;&gt;c__DisplayClass12.&lt;CreateMailboxSession&gt;b__10(MailboxSession mailboxSession)
       at Microsoft.Exchange.Data.Storage.MailboxSession.InternalCreateMailboxSession(LogonType logonType, ExchangePrincipal owner, CultureInfo cultureInfo, String clientInfoString, IAccountingObject budget, Action`1 initializeMailboxSession, InitializeMailboxSessionFailure
    initializeMailboxSessionFailure)
       at Microsoft.Exchange.Data.Storage.MailboxSession.CreateMailboxSession(LogonType logonType, ExchangePrincipal owner, DelegateLogonUser delegateUser, Object identity, OpenMailboxSessionFlags flags, CultureInfo cultureInfo, String clientInfoString,
    PropertyDefinition[] mailboxProperties, IList`1 foldersToInit, GenericIdentity auxiliaryIdentity, IAccountingObject budget)
       at Microsoft.Exchange.Data.Storage.MailboxSession.ConfigurableOpen(ExchangePrincipal mailbox, MailboxAccessInfo accessInfo, CultureInfo cultureInfo, String clientInfoString, LogonType logonType, PropertyDefinition[] mailboxProperties, InitializationFlags
    initFlags, IList`1 foldersToInit, IAccountingObject budget)
       at Microsoft.Exchange.Data.Storage.MailboxSession.OpenAsSystemService(ExchangePrincipal mailboxOwner, CultureInfo cultureInfo, String clientInfoString)
       at Microsoft.Exchange.ProvisioningAgent.MailboxLoggerFactory.XsoMailer.Log(AdminLogMessageData data, LogMessageDelegate logMessage)
       at Microsoft.Exchange.ProvisioningAgent.AdminLogProvisioningHandler.OnComplete(Boolean succeeded, Exception e)</Data>
      </EventData>
    </Event>

    We just ran into this exact problem this morning. At 7:26am the database just dismounted. No errors just dismount. Now they won't mount and we can't run eseutil /p or /d as it immediately errors out. /k works and no errors found.
    Bandaid fix was to go into the EMS and simply move the public and private db to a nas. Now they mount fine. This is strictly a temp solution to get the server back online but something was changed in host machine drive setup (hyperv with compellent san)
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    .. [Database: Mailbox Database 2017935857, Server: xxx.xxx.local].
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