Cannot open Outlook Item .msg

I have a user who cannot open Outlook items (.msg) files. If Outlook is already open I get an error saying "The Operation Failed. The messaging interfaces have returned an unknown error. If the problem persists, restart Outlook." If Outlook is
not already running I get an error that says "Cannot start Microsoft Outlook". I've disabled all add-in's and created a new Outlook profile. I've also saved emails to the desktop and immediately tried to open them and it fails. The user
is running Outlook 2010 version 14.0.6129.5000 32bit on Windows 7 Enterprise 32bit.
The event also generates a system log Event ID 300 from source Microsoft office 14 Alerts.
Microsoft Outlook
The operation failed. The messaging interfaces have returned an unknown error. If the problem persists, restart Outlook.
P1: 301670
P2: 14.0.6029.1000
P3: 6xk3
P4: 0x80004005
Vincent Sprague

First, make sure that Outlook is fully patched and see whether you can repro the issue or not. Then, let us know the following:
Where these .msg files are exist?
How these .msg files are generated?
DeVa, M.S., {MSFT} Please remember to mark the replies as answers if they help

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http://support.microsoft.com/kb/252335
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