Cannot Read or Write to Disk, Error (-50) When re-syncing

Hi,
I'm a little frustrated with my iPod. It syncs just fine when it is first connected to my PC with the usb cable. Then if I add another song or video to be synced and hit 'sync iPod' it will timeout and then return with two errors. First it will say 'an unknown error occurred (-50)' followed by 'Disk cannot be read from or written to'.
I've reset my iPod numerous times and this still happens. I've also deauthorized/authorized my computer and I still get both error messages. I'm running the latest iTunes software and the latest firmware update. My iPod will also sync videos with a mac in the Ipod store, just not with my PC.
Anyone know what's up?
Thanks.
Windows PC Windows XP Pro
Windows PC Windows XP Pro

I did the 5 R's last night, and now my iPod won't update any songs. The iPod is showing up in iTunes, but the "Update iPod" option is grayed out. Also, before when I had installed my iPod, it appeared in iTunes with my name...now it just says IPOD. I assume that's because it's back to the factory settings, but thought it was odd. (Yes, I know how to rename it.)
Actually, after I ran the iPod updater to completely restore my iPod, it sat there frozen for hours with "Do Not Disconnect" on the screen, NOT flashing. Even after I disconnected the iPod (I had to turn off the computer completely to do this; otherwise, the USB port refused to stop running), the message just sat there. I had to reset it to get it to the point where I could select my language.
Any suggestions? I'm considering just wiping out everything (backing up my files, natch) and starting over with the CD that came with the iPod in the first place.
Windows XP

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Cannot Read or Write to Disk, Error (-50) When re-syncing

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