Cannot run FF due to Application security component. What is it?

During download of FF 4.0, saw this block:
"Could not initialize the application's security component. The most likely cause is problems with files in your application's profile directory. Please check that this directory has no read/write restrictions and your hard disk is not full or close to full. It is recommended that you exit the application and fix the problem. If you continue to use this session, you might see incorrect application behaviour when accessing security features."
I have no idea what that means or where to start.

This link shows how to fix this - https://support.mozilla.com/kb/Could+not+initialize+the+browser+security+component

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    This link shows things to check - https://support.mozilla.com/kb/Could+not+initialize+the+browser+security+component

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